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Table 1 Effect of quercetin supplementation on morphometric and metabolic variables in SHR and SHR-Zbtb16 rats

From: Quercetin supplementation in metabolic syndrome: nutrigenetic interactions with the Zbtb16 gene variant in rodent models

Variables

SHR

SHR-Q

SHR-Zbtb16

SHR-Zbtb16-Q

PANOVA

Morphometric variables

   

Initial body weight (g)

393 ± 8χ

383 ± 8χ

387 ± 7χ

352 ± 7αβ

S (0.035), Q (0.015)

Final body weight (g)

404 ± 7χ

396 ± 7χ

393 ± 5χ

347 ± 7αβ

S (0.001), Q (0.003), SxQ (0.024)

Heart (g/100 g b.wt.)

0.44 ± 0.02

0.43 ± 0.01

0.43 ± 0.01

0.41 ± 0.003

n.s.

Liver (g/100 g b.wt.)

3.01 ± 0.1βχ

3.44 ± 0.05β

3.01 ± 0.08αχ

3.50 ± 0.06β

Q (13.10− 6)

Kidneys (g/100 g b.wt.)

0.80 ± 0.01αβχ

0.75 ± 0.01

0.74 ± 0.01

0.72 ± 0.01

S (0.002), Q (0.004)

Adrenals (mg/100 b.wt.)

12.85 ± 0.48χ

13.12 ± 1.16χ

13.35 ± 0.28χ

16.57 ± 0.49αβ

S (0.026), Q (0.045)

Metabolic variables

   

Adiponectin (µg/ml)

0.42 ± 0.09

0.36 ± 0.05

0.46 ± 0.04

0.31 ± 0.03

n.s.

  1. Variables are mean ± SEM, n = 5/6 for each group. The comparison using the post-hoc Fisher’s least significant difference test of the two-way ANOVA for STRAIN (S) and QUERCETIN (Q) as major factors and their interaction SxQ are indicated as follows: α, significantly different compared to SHR-Q; β, significantly different compared to SHR-Zbzt16; χ, significantly different compared to SHR-Zbtb16-Q, p < 0.05. SHR and SHR-Zbtb16: control rats, SHR-Q and SHR-Zbtb16-Q: rats supplemented with quercetin. b.wt.: final body weight