Fig. 4

Overview of gene expression profile in retroperitoneal adipose tissue of quercetin-treated and control SHR (red) and SHR-Zbtb16 (blue) rats. (A) Hierarchical clustering of significantly differentially expressed genes (DEGs). The clustering tree of the gene expression profiles is shown on the left, and the sample clustering tree appears at the top. The color scale indicates the relative gene expression levels, with red representing a high expression level and green, a low expression level. (B) Venn diagram depicting overlapping DEGs among the pair-wise comparisons. (C) The expression of selected genes (qPCR, all validated transcripts are shown in Supplementary Table 3). Values are presented as mean ± SEM (n = 3); p values < 0.05 were considered significant (*p < 0.05, **p < 0.01)