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Table 5 Common DEGs involved in OA pathogenesis in both CGH and CGH-NC vs. CTR groups

From: Effects of the oral administration of glycosaminoglycans with or without native type II collagen on the articular cartilage transcriptome in an osteoarthritic-induced rabbit model

  

CGH-NC vs. CTR

CGH vs. CTR

Gene Symbol

Associated Protein

p-value

Fold-Change

UP/

DOWN

p-value

Fold-Change

UP/

DOWN

Fgf10

Fibroblast growth factor 10

0.0001

-1.367

DOWN

0.004

-1.300

DOWN

Adamts9

ADAM metallopeptidase with thrombospondin type 1 motif, 9

0.005

-1.127

DOWN

0.002

-1.163

DOWN

Chsy3

Chondroitin sulfate synthase 3

0.004

1.228

UP

0.002

1.195

UP

Il16

Interleukin 16

0.003

1.751

UP

0.0002

1.772

UP

Acan

Aggrecan

0.003

1.951

UP

0.003

2.495

UP

Aldh6a1

Aldehyde dehydrogenase 6 family, member A1

0.001

1.450

UP

0.002

2.479

UP

  1. Common OA pathogenesis-related DEGs (p < 0.005) in both CGH-NC and CGH groups (Student’s t test), sorted by Fold-Change