Fig. 2

Regional locus association plot showing −log10 (P values) for the serum Mg²⁺-associated regions near (A) TRIM46 and MUC1 gene on chr1, (B) SHROOM3 and CCDC158 gene on chr4, (C) SLC22A7 and ZNF318 gene on chr6, and (D) TAF3 gene on chr10. Top panel shows the P value (−log10) for each SNP. The colors of the points indicate the linkage disequilibrium with the top signal indicated by the diamond. The blue line represents the recombination rate. The middle panel shows the location of the SNP indicated by a blue line and the lower panel shows the genes in the region. Chr = chromosome, Mg²⁺ = magnesium