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Table 3 List of non-retained compounds for stone fruit

From: Food intake biomarkers for apple, pear, and stone fruit

Food item

Compound

PhytoHub ID

HMDB ID

Biofluid

Reasons for exclusion

References

Cherry

Cyanidin 3-rutoside,

cyanidin 3-O-glucoside,

cyanidin-3-glucosylrutinoside

PHUB000504 PHUB000503 PHUB001606

HMDB0031458 HMDB0030684 HMDB0037988

Plasma, urine

Common to many anthocyanin-rich foods; very low concentrations even after acute intake; very transient increase (< 2 h)

[79]

Cherry

6-Sulfatoxymelatonin

PHUB001884

HMDB0041815

Urine

Main metabolite of melatonin; common to all melatonin-rich foods. Also endogenous origin, affected by many factors (age, BMI, smoking…)

[84, 85]

Cherry

5-Hydroxyindoleacetic acid

PHUB001475

HMDB00763

Urine

Main metabolite of serotonin; common to all serotonin-containing foods such as banana, pineapple, and walnut; also endogenous origin

[88]

Plum

Anthocyanins:

peonidin 3-glucoside,

peonidin 3-rutoside,

cyanidin monoglucuronide

PHUB001257;

PHUB001296;

HMDB13689

Urine

Present in other berries, drupes, and red wine. Very low concentration and short half-life

[96]

Plum

Hippuric acid

PHUB001174

HMDB00714

Urine

Very common metabolite of polyphenols with many possible origins; not specific

[96]

Plum

Caffeic acid

PHUB000574

HMDB01964

Plasma, urine

Widely distributed in plant foods; not specific

[92]

Plum

5-Hydroxymethyl-2-furoic acid,

(5-carboxylic acid-2-furoyl)glycine

PHUB001892

PHUB001894

Plasma, urine

Metabolites of 5-hydroxymethylfurfural (HMF), also present in coffee, dried fruit, fruit juices and honey

[93]

Cherry

Hydroxycinnamic acids:

caffeic acid,

ferulic acid,

p-coumaric acid, vanillic acid

PHUB000574

PHUB000608

PHUB000316

HMDB0001964

HMDB0000954

HMDB0000484

Plasma

Widely distributed in plant foods; not specific

[97]

  1. Abbreviations: HMDB ID human metabolome database identification number, http://www.hmdb.ca; PhytoHub ID: http://phytohub.eu/